Evidence-based research on nootropics and nutrients that support memory, focus, and long-term cognitive resilience.
In Brief Safety: 40Hz flickering light can trigger seizures in people with photosensitive epilepsy. If you have a history of seizures or migraines, do not use this therapy without direct neurological supervision. Effectiveness: Clinical trials, including those from MIT,…
In Brief Safety: L-Theanine is generally recognized as safe (GRAS), but high doses of caffeine can worsen ADHD impulsivity or anxiety. Those with genetic slow caffeine metabolism (CYP1A2) should limit intake to before noon. Effectiveness: Clinical trials demonstrate that…
In Brief Safety: Phosphatidylserine acts as a mild blood thinner. If you take Warfarin or Heparin, you must consult your doctor to prevent bleeding risks. Effectiveness: It is one of the few supplements with an FDA “Qualified Health Claim”…
In Brief Safety: Alpha GPC has been linked to a 46% higher risk of stroke in a 10-year cohort study due to TMAO spikes. Citicoline does not carry this specific risk profile. Effectiveness: Alpha GPC crosses the blood-brain barrier…
In Brief Safety: Most natural nootropics affect neurotransmitters. If you take antidepressants or anxiety medication, consult a doctor to avoid “Serotonin Syndrome.” Effectiveness: Clinical data shows that L-Theanine combined with caffeine improves accuracy on attention-switching tasks by reducing error…
In Brief Safety: Most natural remedies are low-risk, but always check with a doctor if you are on blood thinners or have kidney issues before starting supplements. Effectiveness: Clinical data links chronic brain fog to neuroinflammation, suggesting that anti-inflammatory…
In Brief Safety: Generally safe, but it may slow blood clotting. Stop taking it two weeks before surgery. Effectiveness: Clinical trials show significant cognitive improvements in adults with mild impairment after 16 weeks of consistent use. Key Benefit: Stimulates…
In Brief Safety: Both forms are generally safe and well-tolerated, with fewer gastrointestinal side effects than cheap forms like magnesium oxide. Effectiveness: Threonate excels at crossing the blood-brain barrier for cognitive support, while glycinate is superior for overall systemic…
In Brief Safety: Generally safe but quality and dosage are critical to avoid adverse effects. Effectiveness: Efficacy varies wildly based on the specific nutrient and its bioavailability. Key Benefit: Targeted nutrients can support brain cell structure and reduce oxidative…
In Brief Safety: Most lifestyle changes are highly safe, but herb-drug interactions exist. Effectiveness: Consistency with diet, sleep, and exercise shows the most robust clinical backing. Key Benefit: Addresses root causes like inflammation and blood flow rather than just…