Evidence-based nutritional strategies for managing health challenges, from metabolic support to cognitive performance and vitality.
In Brief Safety: Sarsasapogenin, the active phytosterol in Volufiline, interacts with fat cells but does not bind to estrogen receptors. It is considered safe for topical use, though the base oil (often hydrogenated polyisobutene) can cause breakouts in acne-prone…
In Brief Safety: High-dose Zinc (over 40mg daily) induces copper deficiency by competing for absorption. Monitor for anemia or neurological symptoms if using this protocol long-term. Effectiveness: Research shows Quercetin acts as a natural ionophore, increasing intracellular Zinc concentrations…
In Brief Safety: Oral micronized progesterone is contraindicated in women with active liver disease or unexplained vaginal bleeding. Monitor for severe drowsiness if taking oral doses during the day. Effectiveness: Vaginal administration achieves significantly higher uterine tissue concentrations with…
In Brief Safety: Lutein is generally recognized as safe (GRAS), though high chronic doses can cause harmless yellowish skin discoloration. Current clinical evidence shows no adverse effects in children or adults at standardized doses. Effectiveness: Research indicates that daily…
In Brief Safety: Magnesium is cleared by the kidneys. If you have Chronic Kidney Disease (CKD), high doses can lead to hypermagnesemia, which causes low blood pressure and cardiac arrest. Consult a nephrologist before supplementing. Effectiveness: Clinical data shows…
In Brief Safety: Benfotiamine is generally well-tolerated. It converts to Thiamine in the body, which has no established Upper Tolerable Limit because excess is excreted. However, rare cases of sulfur sensitivity can cause skin rashes. Effectiveness: Clinical data shows…
In Brief Safety: Benfotiamine is synthetic but converts to natural Thiamine in the body. It is generally safe, though high doses can cause a harmless “sulfur” odor in sweat. Rare allergic skin reactions have been documented. Effectiveness: Clinical pharmacokinetics…
In Brief Safety: Berberine inhibits CYP liver enzymes. This can potentiate (increase the strength of) medications like statins or beta-blockers. Phytosome forms are absorbed more efficiently, potentially increasing this interaction risk. Effectiveness: Clinical data indicates that Berberine Phytosome achieves…
In Brief Safety: Black Pepper Extract (Piperine) inhibits the liver’s CYP3A4 enzymes. This boosts curcumin absorption but also prevents the breakdown of many prescription drugs, potentially leading to overdose. Micellar forms do not have this drug-interaction risk. Effectiveness: Clinical…
In Brief Safety: High doses of antioxidants like Vitamin E (above 400 IU) can increase bleeding risk. If you are on blood thinners or have a surgery scheduled, consult your doctor before starting a hearing protection protocol. Effectiveness: The…